I remembered two times where i used the fourth wall, back in high school when i was working on a comic called Nameless and Aimless. Which i love by the way, i still laugh at the jokes, this is a good sign. At one point, i set fire to my room (another story for another day) and the dialogue went something like this:
Hat guy: man, this comic books smells like smoke!
Armor guy: yeah, the author set his room on fire, almost lost us and all.
Hat guy: what? why would he do that?
The Author walks into the frame, waving his arms angrily at the two.
Author: guys! you're not sticking to the script!
Hat guy: you almost set us on fire!
The Author takes out an eraser.
Author: now, are you guys going to behave or am i going to have to use...the eraser?
Armor guy punches the Author in the face.
Yeah, i had fun in high school :P